Uses of Glucose Oxidase in medical science

Glucose Oxidase is a really critical enzyme with hundreds of applications in dozens of industries. In this article we'll be discuss that what Glucose Oxidase is, what it does and exactly why this little enzyme is very  important to so many people.

    

Also known as "GOx", Glucose Oxidase is a naturally happen oxido-reductase enzyme which causes the oxidation of glucose, change it into hydrogen peroxide. Structurally, this is a dimeric protein and, as is the case with the maximum  of proteins which work on cells outer, it is coated with carbohydrate chains to break down sugars into.

In cells, the main  function of Glucose Oxidase is  their metabolites. The enzyme happen naturally in honey where it doe as a natural preservative. This is due to GOx creates an "antimicrobial barrier" on the honey's surface. This antimicrobial barrier is produce when GOx on the surface of the honey reduces atmospheric Oxygen to Hydrogen Peroxide (H2O2). The antibacterial properties of honey are well resistered as can be seen in the use of the substance as a key subtances in natural skincare. Its success is all down to Glucose Oxidase! But this is not all that it does. Most importantly GOx creates a colour reaction to H2O2 when it is mixed with a peroxidase reaction. This allows the medical and scientific establishment to know and measure the quantities of free glucose (sera) in blood plasma.

Glucose Oxidase only happen naturally in small quantities. Although due to its usefulness in such a various range of industries, it is now produce on a large scale. The way for production is relatively simple: When a fungus known as Aspergillus Niger is changed it produce    s Glucose Oxidase. Primarily the liquid from the fermented fungus is not suitable for use as such an enzyme but, after purification it is usable. The liquid is purified using variousl processes: multiple precipitation; fractionation; chromatography; and filtration. For every 200 litres of liquid produced by the fermentation process, a few kilograms of freeze-dried Glucose Oxidase is produced.